Detection of resistance to second - line antituberculosis drugs using the Genotype ® 1 MTBDR sl assay : a multi - center evaluation and feasibility study

Detection of resistance to second-line antituberculosis drugs using the Genotype® 1 MTBDRsl assay: a multi-center evaluation and feasibility study. 2 3 Olga Ignatyeva, Irina Kontsevaya, Alexander Kovalyov, Yanina Balabanova, Vladislav 4 Nikolayevskyy, Kadri Toit, Anda Dragan, Daniela Maxim, Svetlana Mironova, Tiina 5 Kummik, Ionela Muntean, Ekaterina Koshkarova, and Francis Drobniewski 6 7 1 – Samara Oblast Tuberculosis Dispensary, Samara, Russia; Address: Samara Oblast 8 Tuberculosis Dispensary: 154, Novo-Sadovaya str., Samara, Russia, 443068 9 2 Queen Mary College, Barts and the London School of Medicine, University of London, 10 London, UK; Address: 2 Newark Street, London E1 2AT, UK. 11 3 Tartu University Hospital, Tartu, Estonia; Address: Puusepa 1a, 50406 Tartu, Estonia 12 4 Pneumophtisiology Hospital, Brasov, Romania; Address: 12, Aleea Dealul Spirii Brasov 13 Jud. Brasov 500118, Romania 14 5 Pneumophtisiology Institute Nasta, Bukharest, Romania. Address: Sos. viilor 90, sector 5, 15 Bucharest, Romania, 050189. 16 § Olga Ignatyeva and Irina Kontsevaya have equally contributed to the manuscript. 17 18 # Correspondence to: Francis Drobniewski, e-mail: [email protected] 19 20